The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

• Work closely within a highly collaborative and multidisciplinary team of chemists, biochemists, structural biologists, and cell biologists
• Provide medicinal chemistry support during hit validation and lead optimization

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a PhD degree from an accredited college or university according to the Council for Higher Education Accreditation (CHEA) or eight (8) years of related experience. Foreign degrees must be evaluated for U.S. equivalency
• No work experience required with a Doctorate degree
• Ability to keep accurate records of experiments and data
• Capable of presenting findings at regular team meetings
• Must be highly collaborative, self-motivated, and team-oriented
• Must have excellent oral and written communication skills
• Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• A minimum of 3 years of postdoctoral experience in organic chemistry or a related field
• Expertise in the design, synthesis, and characterization of pharmaceutically relevant small molecules
• Knowledge of medicinal chemistry, drug discovery, and compound progression
• Experienced in multistep organic synthesis and the handling of air/moisture sensitive materials
• Familiarity with modern analytical technologies including: LCMS, NMR (1H, 13C, 2D techniques), HPLC, and Flash chromatography
• Basic knowledge of cancer biology

JOB HAZARDS

This position is subject to working with, or has potential for exposure to infectious material, requiring medical clearance and immunizations.

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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