Research Associate - MASS Spectrometry Proteomics
October 9, 2022
Research Associate - MASS Spectrometry Proteomics
Job ID: req2621
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.
KEY ROLES/RESPONSIBILITIES
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
JOB HAZARDS
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
#readytowork
Job ID: req2621
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. In addition, the CRTP hosts the Nanotechnology Characterization Laboratory (NCL) which performs and standardizes preclinical efficacy and toxicity testing of nanoparticles intended for cancer therapeutics and diagnostics, and the Antibody Characterization Lab (ACL) which characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research. CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise.
KEY ROLES/RESPONSIBILITIES
- Work independently and collaboratively with scientists to perform liquid chromatographic mass spectrometry (LC-MS)-based proteomics experiments, including: protein extraction, immunoprecipitation, protein digestion, solid-phase extraction (SPE), SDS-PAGE, buffer preparation, etc. following established SOPs
- Analyze large, complex data sets using spreadsheets, access, and/or other data analysis packages (R or Python)
- Establish (design, test, and write) new or modify/optimize existing detailed technical SOPs
- Document experimental results in a reproducible manner
- Maintain lab supplies, equipment, and inventories
- Analyze, interpret, and effectively present data to team members and collaborators
- Comply with all safety procedures and policies
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
- Possession of a Bachelor's degree in chemistry/biochemistry from an accredited college or university according to the Council for Higher Education Accreditation (CHEA). (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
- Level I - In addition to education requirements, a minimum of two (2) years of laboratory experience
- Level II - In addition to education requirements, a minimum of five (5) years of laboratory experience
- Experience with large, complex data set analysis using programs such as: Excel, Word, Power Point, R, or Python
- Detail-oriented, highly-collaborative, self-motivated, and team-oriented
- Excellent communication skills
- Ability to obtain and maintain a security clearance
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
- Familiar with Mass Spectrometry software for mass spectrometer operation and/or data analysis
- Experience with troubleshooting/optimizing sample protocols and/or lab equipment
- Experience or good knowledge of LC-MS-based proteomic experiments, including either Orbitrap global proteomics mass spectrometry and/or Triple Quad targeted proteomics mass spectrometry
- Experience with sample preparation for bottom-up proteomics studies (global or targeted)
JOB HAZARDS
- This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations
Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)
#readytowork