Research Associate I, Next Generation Sequencing

Job ID: req2757
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI's intramural Center for Cancer Research (CCR). The dedicated units provide expertise in electron microscopy, protein characterization, mass spectrometry, protein expression, optical microscopy, and genomics. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR), where CRTP scientists work collaboratively with intramural NCI investigators to provide research technologies and expertise.

KEY ROLES/RESPONSIBILITIES

• The Sequencing Facility is a high throughput laboratory providing cutting edge next generation technologies to the National Cancer Institute. Current platforms include the Illumina NovaSeq, NextSeq, MiSeq, PacBio and additional platforms in the future. All projects are of a highly specialized nature and require technical proficiency, problem solving skills and good judgment.
• The candidate will be responsible for assisting with next generation (NGS) sequencing for the core facility. Responsible for all ongoing daily activities including library prep and sequencer set up, maintenance of equipment, use of protocols, sample quality control and troubleshooting of problems with direct coordination of the supervisor.
• Requires adherence to strict safety protocols and may require the use of personal protective equipment.

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a (CHEA) Bachelor degree from an accredited college or university according to the Council for Higher Education Accreditation. (Additional qualifying experience may be substituted for the required education). Foreign degrees must be evaluated for U.S. equivalency
• In addition to the education requirement, a minimum of 2 years related experience
• Strong background in cell and molecular biology with familiarity of next generation sequencing methods
• Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• Hands-on experience with next-generation sequencing
• Experience working in a core facility or other team-based environment
• Demonstrated ability to learn new technologies quickly and ability to assist in new protocol development
• Familiarity with diverse sample types and processing methods
• Working knowledge of DNA hybridization, ligation, fragmentation, endpolishing, PCR, automation using robotics, Agilent Bioanalyzer, nanodrop, qPCR, sterile/clean room techniques, and sample and process tracking through LIMS is also required. The ideal candidate must have the ability to organize and utilize reagents and samples for high-throughput analysis in support of genomic studies and two years proven experience in DNA sequencing, data review and stringent record keeping
• Must have excellent written and verbal communication skills
  
• Must be detail-oriented, and able to manage multiple projects simultaneously

JOB HAZARDS

• This position is subject to working with or have potential for exposure to infectious material, requiring
  medical clearance and immunizations

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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