Research Associate III

Job ID: req2976
Employee Type: exempt full-time
Division: Applied & Development Research Program
Facility: Frederick: Ft Detrick
Location: PO Box B, Frederick, MD 21702 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION

The Frederick National Laboratory for Cancer Research (FNL) is a Federally Funded Research and Development Center sponsored by the National Cancer Institute (NCI) and operated by the prime contractor Leidos Biomedical Research, Inc. FNL is responsible for pursuing a unique mission in translational and applied biomedical research that is unsuitable for academia, the pharmaceutical industry, or other federal contractors.

The selected candidate will join the NCI Division of Cancer Treatment and Diagnosis (DCTD) support group located at the NCI-Frederick campus. This program supports the NCI DCTD by providing radiopharmaceuticals for clinical trials and preclinical studies, developing new radiopharmaceuticals, and providing regulatory affairs support. Activities include production and/or procurement of investigational and experimental radiopharmaceuticals; contributing to the advanced development of the DCTD- and non-DCTD-sponsored investigational radiopharmaceuticals; supporting clinical trials; and providing nuclear medicine sites with access to DCTD radiopharmaceuticals.

The successful candidate will support the investigation of radiopharmaceuticals by setting-up and executing various biomarker assays chosen to elucidate mechanisms of radiopharmaceutical uptake. In addition, they will support the development and execution of QC testing of radiopharmaceuticals and contribute to radiopharmaceutical production.

KEY ROLES/RESPONSIBILITIES

• Set-up and verify various biomarker assays as required to support PET radiopharmaceutical studies
• Perform biomarker assays on cellular and tissue samples
• Perform quality control testing of radiopharmaceuticals (e.g., HPLC, GC, TLC, pH, bubble testing, etc.)
• Comply with regulatory requirements for execution of biomarker assays and production/QC of radiopharmaceuticals as detailed in FNL Standard Operating Procedures (SOPs)
• Qualify and maintain QC equipment
• Contribute to cGMP compliance of facility through activities including cleaning, environmental monitoring, gowning, accurate completion of documentation, creation of exception reports
• Support the development of new QC methods including novel HPLC, GC, and TLC QC methods
• Maintain inventory of lab supplies, as needed, to support laboratory activities
• Assist the Laboratory Manager/Supervisor with record keeping and reporting to comply with rules and regulations that apply to the use of radioisotopes
  

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of a Bachelor's degree from an accredited college or university (according to CHEA) in a field related to biomedical research. Foreign degrees will be evaluated for U.S. equivalency
• Minimum of eight (8) years relevant experience in analytical method development and execution or related field
• Willingness to work with radioactivity
• Excellent verbal and written communication skills
• Ability to obtain and maintain a security clearance
  

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:

• Experience developing novel analytical methods
• Experience working with biological samples (cells, tissues)
• Willingness to learn new skills (e.g. automated radiopharmaceutical production)
• Experience working in a regulated environment (such as cGMP-like)

JOB HAZARDS

• This position is subject to working with or have potential for exposure to animal(s)
  and/or animal material(s)
• This position is subject to working with or have potential for exposure to animal(s)
  and/or animal material(s)
• This position is subject to working with or have potential for exposure to infectious
  material, requiring medical clearance and immunizations
• This position is subject to atmospheric conditions that would require the usage of a
  respirator, requiring a medical clearance
• This position is subject to working with radioactive material and requires to become
  an approved radiation worker

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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