Cell Culture Associate

November 15, 2022
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Cell Culture Associate

Job ID: req3014
Employee Type: exempt full-time
Division: Cancer Research Technology Program
Facility: Frederick: ATRF
Location: 8560 Progress Dr, Frederick, MD 21701 USA

The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.

PROGRAM DESCRIPTION

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community. A major focus of the CRTP is the NCI RAS Initiative with the goal to discover new therapeutic interventions against RAS-driven cancers. As part of the RAS Initiative, the Protein Expression Laboratory (PEL) generates protein reagents to support internal and external RAS-related research. PEL staff utilize a variety of cutting-edge protein production methods including expression in a wide variety of host platforms to generate high-quality protein reagents used for structural biology and drug discovery.

KEY ROLES/RESPONSIBILITIES
  • Carry out experiments, under the review of a scientist, in areas of eukaryotic cell culture and protein production
  • Perform expression in insect and mammalian cell culture systems, including HEK293 and CHO cells
  • Generate small-scale protein purification data to enable optimization of protein production
  • Carry out purification of secreted proteins from eukaryotic cell culture supernatants
  • Perform quality control on purified proteins
  • Participate on project teams, present data and discuss experimental results

BASIC QUALIFICATIONS

To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
  • Possession of Bachelor's degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency.
  • In addition to the education requirement, a minimum of two (2) years of progressively responsible experience
  • Ability to handle multiple scientific projects with a high degree of accuracy
  • Ability to follow and apply standard laboratory production protocols and procedures
  • Excellent oral and written communication skills
  • Ability to obtain and maintain a security clearance

PREFERRED QUALIFICATIONS

Candidates with these desired skills will be given preferential consideration:
  • Experience with Microsoft Office and Filemaker software
  • Prior experience with cell culture and sterile technique
  • Prior experience with protein production

JOB HAZARDS
  • This position is subject to working with or have potential for exposure to infectious
    material, requiring medical clearance and immunizations


Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW)

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