Research Associate I, HPV Genomics Team, CGR
September 13, 2023
Research Associate I, HPV Genomics Team, CGR
Job ID: req3724
Employee Type: exempt full-time
Division: Clinical Research Program
Facility: Rockville: 9615 MedCtrDr
Location: 9615 Medical Center Drive, Rockville, MD 20850 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world's most comprehensive cancer epidemiology research group. CGR is located at the NCI-Shady Grove campus in Rockville, MD and operated by Leidos Biomedical Research, Inc. We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG. Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG's intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. This includes the design and analysis of high throughput studies using various types of "-omics" technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome. We are seeking a Research Associate to join our team to support studies that influence global decisions on HPV vaccine expansion and dosing recommendations and will have a direct impact on human health to enable prevention or early-detection of cervical cancer.
KEY ROLES/RESPONSIBILITIES
Within CGR, the Genomics Laboratory is a fast-paced, high-throughput, genotyping and sequencing facility dedicated to the support of genetic and epidemiologic studies for investigators at the National Cancer Institute. We are recruiting for Research Associate I position to be part of an independent group focused on HPV (human papillomavirus) research within the Genomics Laboratory. The successful candidate will be responsible for performing high-throughput viral sequencing and epigenomic assays. Consistent generation of high-quality data from these assays is a critical component of large-scale studies that will influence recommendations for global vaccination strategies. Key responsibilities include:
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.
#readytowork
Job ID: req3724
Employee Type: exempt full-time
Division: Clinical Research Program
Facility: Rockville: 9615 MedCtrDr
Location: 9615 Medical Center Drive, Rockville, MD 20850 USA
The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.
Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it's the FNL way.
PROGRAM DESCRIPTION
The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI's Division of Cancer Epidemiology and Genetics (DCEG), the world's most comprehensive cancer epidemiology research group. CGR is located at the NCI-Shady Grove campus in Rockville, MD and operated by Leidos Biomedical Research, Inc. We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70+ investigators in DCEG. Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG's intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. This includes the design and analysis of high throughput studies using various types of "-omics" technologies such as array- and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome. We are seeking a Research Associate to join our team to support studies that influence global decisions on HPV vaccine expansion and dosing recommendations and will have a direct impact on human health to enable prevention or early-detection of cervical cancer.
KEY ROLES/RESPONSIBILITIES
Within CGR, the Genomics Laboratory is a fast-paced, high-throughput, genotyping and sequencing facility dedicated to the support of genetic and epidemiologic studies for investigators at the National Cancer Institute. We are recruiting for Research Associate I position to be part of an independent group focused on HPV (human papillomavirus) research within the Genomics Laboratory. The successful candidate will be responsible for performing high-throughput viral sequencing and epigenomic assays. Consistent generation of high-quality data from these assays is a critical component of large-scale studies that will influence recommendations for global vaccination strategies. Key responsibilities include:
- Perform high-throughput HPV typing, screening, and methylation assays using Next-Generation Sequencing technology
- Meet expected schedules and performance expectations in a fast-paced research laboratory environment
- Utilize good laboratory practices, aseptic techniques, and molecular biology expertise to ensure that highly sensitive PCR-based assays are performed successfully
- Follow established protocols and assist with deviations and corrective actions
- Accurately maintain thorough documentation
- Routine maintenance, operation and troubleshooting of laboratory equipment used
- Support a culture of continuous improvement and accountability
- Support troubleshooting of issues associated with assay processing
- Participate in the writing and review of laboratory SOPs
BASIC QUALIFICATIONS
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
- Possession of a Bachelor's degree from an accredited college or university according to the Council for Higher Education Accreditation
- In addition to educational requirements, a minimum of two (2) years related biomedical experience
- Experience with aseptic and basic molecular biology laboratory techniques
- Strong understanding of molecular biology
- Careful attention to detail
- Critical thinking skills and ability to identify important variables in an experiment
- Collaborative, team-oriented approach to solving problems and achieving goals
- Strong organization skills, ability to multitask and manage time effectively
- Excellent communication skills (verbal and written)
- Working knowledge of Windows-based computer operating systems and Microsoft Office suite
- Must be able to obtain and maintain a clearance
PREFERRED QUALIFICATIONS
Candidates with these desired skills will be given preferential consideration:
- Experience performing, troubleshooting, and optimizing PCR, NGS, or other molecular biology assays
- Experience using high-throughput laboratory equipment, such as automated liquid handlers, including use, maintenance, and troubleshooting
- Familiarity with eLN and/or LIMS systems for sample and workflow tracking
- Expertise with a wide range of specimen types and analytes used in genomics
Commitment to Diversity
All qualified applicants will receive consideration for employment without regard to sex, race, ethnicity, age, national origin, citizenship, religion, physical or mental disability, medical condition, genetic information, pregnancy, family structure, marital status, ancestry, domestic partner status, sexual orientation, gender identity or expression, veteran or military status, or any other basis prohibited by law. Leidos will also consider for employment qualified applicants with criminal histories consistent with relevant laws.
#readytowork